Harmonized TARGET Data Released in the NCI GDC Data Portal
The NCI Genomic Data Commons (GDC) includes the data that the TARGET project has created. GDC harmonizes TARGET data using GDC alignment and variant calling pipelines and makes the harmonized data available in the GDC Data Portal.
The GDC applies multiple variant calling pipelines for the somatic variant calls in the Variant Call Format (VCF). They plan to release new aggregated mutations in the Mutation Annotation Format (MAF) for each sample in the near future. The currently available MAFs do not reflect the VCF updates. Additional details are available in the GDC Data Release Notes.
The TARGET Initiative produces large-scale genomic data for a set of pediatric cancers and provides the research community access to those data. The goal for broadly sharing TARGET data is to facilitate the discovery of therapeutic targets for childhood cancers and catalyze the translation of these discoveries into clinical applications.
Learn how to search and download TARGET data by reading the sections below.
- About the Data – Explains the types of data provided by TARGET
- Open vs. Controlled TARGET Data – Explains the types of data that are openly available and those that require Data Use Certification (i.e. approval)
- How to Access Protected Data – Provides step-by-step instructions for how to access controlled TARGET data
- How to Navigate the TARGET Data Matrix – Describes the Data Matrix and how it is organized