News & Publications

OCG is committed to sharing its research with the community. Stay informed by reading the latest news & publications and subscribing to the OCG e-Newsletter.

Publications

Diagram showing cancer cells spreading into the blood stream CRUK 448
CTD²
Blood

Much of what is known about the neurotrophic receptor tyrosine kinase (NTRK) genes in cancer was revealed through identification and characterization of activating Trk fusions across many tumor types. A resurgence of interest in these receptors has emerged owing to the realization that they are...

Mitochondrial Dynamics in Pancreatic Cancer
CTD²
Nature Chemical Biology

Doublecortin like kinase 1 (DCLK1) is an understudied kinase that is upregulated in a wide range of cancers, including pancreatic ductal adenocarcinoma (PDAC). However, little is known about its potential as a therapeutic target. We used chemoproteomic profiling and structure-based design to...

e-Newsletter

Issue 23, December, 2019

Featured Researchers

Headshot of Dr. Andy Mungall
Interviewed by Cindy Kyi, Ph.D.
Last updated: July 29, 2020