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Graphical Abstract Zhao et al. (2020) Cancer Cell.
Cancer Cell

Perturbation biology is a powerful approach to modeling quantitative cellular behaviors and understanding detailed disease mechanisms. However, large-scale protein response resources of cancer cell lines to perturbations are not available, resulting in a critical knowledge gap. Here we generated...

Brain, Medial, Child, Anatomy-CNS Germ Cell Tumor-HP
Cancer Research

Medulloblastoma (MB) is among the most common malignant brain tumors in children. Recent studies have identified at least four subgroups of the disease that differ in terms of molecular characteristics and patient outcomes. Despite this heterogeneity, most MB patients receive similar therapies,...


Issue 24, August, 2020

HCMI Program Highlights

Banner for Human Cancer Model Initiative
Eva Tonsing-Carter, Ph.D. and Cindy Kyi, Ph.D.
Last updated: November 25, 2020