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Poster Presentation at Virtual AACR Annual Meeting 2021

June 04, 2021

TARGET

Working Towards Greater Precision in Childhood Cancers

March 07, 2018

HCMI

Office of Cancer Genomics launches new program

July 11, 2016

Publications

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CTD²

A CRISPR/Cas9-Engineered ARID1A-Deficient Human Gastric Cancer Organoid Model Reveals Essential and Nonessential Modes of Oncogenic Transformation*

Cancer Discovery

Mutations in ARID1A rank among the most common molecular aberrations in human cancer. However, oncogenic consequences of ARID1A mutation in human cells remain poorly defined due to lack of forward genetic models. Here, CRISPR/Cas9-mediated ARID1A knockout (KO) in primary TP53^-/- human...

CTD²

Single-cell protein activity analysis identifies recurrence-associated renal tumor macrophages

Cell

Clear cell renal carcinoma (ccRCC) is a heterogeneous disease with a variable post-surgical course. To assemble a comprehensive ccRCC tumor microenvironment (TME) atlas, we performed single-cell RNA sequencing (scRNA-seq) of hematopoietic and non-hematopoietic subpopulations from tumor and tumor...

Last updated: June 09, 2021